Zhaohai Li, Ph.D.

Dr. Li is a Professor of Statistics and Biostatistics in the Department of Statistics. He is the Director of Biostatistics Graduate Program. The Biostatistics Graduate Program is co-sponsored by the Biostatistics Center, the Department of Epidemiology and Biostatistics in the School of Public Health and Health Services, and the Department of Statistics in the Columbian College of Arts and Sciences.


Selected Recent Publications:

Buckman DW and Li Z. Missing Data Methods for Linkage Analysis of IBS and Incomplete IBD from Affected Sib-pairs.  Statistics and Its Interface, 2:  133-144, 2009

She D, Zhang H, and Li Z. Testing Hardy-Weinberg Equilibrium using Family Data from Complex Survey. Annals of Human Genetics, 73: 449-455, 2009

Zhang H, Chen H, and Li Z. Large Sample Interval Mapping of Trait Loci in Finite Regression Mixture Models. Journal of Statistical Planning and Inference, 139: 764-779, 2009

Cui W, Zhang H, Yang Y, and Li Z. Linkage Analysis with Mixed Sample of  Affected Full and Half Sib-pairs in the Presence of Uncertain Relationship. In Frontiers of Biostatistics and Bioinformatics, University of Science and Technology of China Press, Edited by Ma S and Wang Y, 3-15, 2009

Li Z, Zhang H, Zheng G, Gastwirth JL, and Gail MH. Excess False Positive Rate Caused by Population Stratification and Disease Rate Heterogeneity in Case-Control Association Studies. Computational Statistics and Data Analysis, 53: 1767-1781, 2009.

Shu Y, Liu A, and Li Z. Point and Interval Estimates of Accuracies of a Binary Medical Diagnostic Test in Group Sequential Designs. Philosophical Transactions of the Royal Society A, 366: 2335-2345, 2008.

Yan L K, Zheng G, and Li Z. Controlling Type I Error in Two-Stage Group Sequential Robust Tests in Family-based Association Studies. Annals of Human Genetics, 72: 557-565, 2008.

Li Q, Yu K,  Li Z, and Zheng G. MAX-Rank: A Simple and Robust Genome-Wide Scan for Case-Control Association Studies. Human Genetics, 123: 617-623, 2008.

Zhang H, Chen H, and Li Z. An Explicit Representation of the Limit of the LRT for Interval Mapping of Quantitative Trait Loci. Statistics & Probability Letters, 78: 207-213, 2008.

Chen X and Li Z. Inference of Haplotye Effects in Case-Control Studies Using Unphased Genotype and Environmental Data. Biometrical Journal, 50: 270-282, 2008.

Li Q, Zheng G, Li Z, and Yu K. Efficient Approximation of P-value of Maximum of Correlated Tests with Applications to Genome-Wide Association Studies. Annals of Human Genetics, 72: 397-406, 2008.

Zhang H, Zhang H, Li Z, and Zheng G.  Statistical Methods for Haplotype-based  Matched Case-control Association Studies. Genetic Epidemiology, 31: 316-326, 2007.

Shu Y, Liu A, and Li Z. Two-Stage Evaluation of Sensitivity and Specificity in Binary Diagnostic Tests. Statistics in Medicine, 26: 4416-4427, 2007.

Qin H, Zhang H, and Li Z. The Impact of Population Stratification on Population-based QTL Association Studies. Random Walk, Sequential Analysis and Related Topics – A Festschrift in Honor of Yuan-Shih Chow, Edited by Agnes Hsiung, Cun-Hui Zhang, and Zhiliang Ying, World Scientific Publisher, Singapore, page: 311-333, 2006.

Li Z, Qin H, and Zhang H. Statistical Methods for Genetic Analysis. Science Press, Beijing, China, 2006.

Deng W, Chen H, and Li Z. A Logistic Regression Mixture Model for Interval Mapping of Genetic Trait Loci Affecting Binary Phenotypes. Genetics, 172: 1349-1358, 2006

Zheng G, Ghosh K, Chen Z, and Li Z. Extreme Rank Selection for Linkage Analysis of Quantitative Trait Loci Using Selected Sib-pairs. Annals of Human Genetics, 70: 857-866, 2006.

Zhang H, Zheng G, and Li Z. Statistical Analysis for Haplotype-Based Matched Case – Control Studies. Biometrics, 62: 1124-1131, 2006.

Chen Z, Zheng G, Ghosh K, and Li Z. Linkage Disequilibrium Mapping of Quantitative Trait Loci by Selective Genotyping. American Journal of Human Genetics, 77: 661-669, 2005.

Li Z, Gastwirth JL, and Gail MH. Power and Related Statistical Properties of Conditional Likelihood Score Tests for Association Studies in Nuclear Families with Parental Genotypes. Annals of Human Genetics, 69: 296-314, 2005.


 

Contact information

Department of Statistics
The George Washington University
2140 Pennsylvania Ave., N.W.
Washington, DC 20052

Phone: 202-994-7844
Fax: 202-994-6917
Email: zli@gwu.edu