PERSONAL             Date of birth:  January 24, 1943
 DATA                      Married with two children

 BUSINESS               Department of Forensic Sciences
 ADDRESS                The George Washington University
                                 Washington, DC  20052
                                 (202) 994-1468

 DEGREES                 Ph.D.
 HELD                       Pharmaceutical Chemistry
                                  Duquesne University 1975

                                  M.S.
                                  Pharmacology / Toxicology
                                  Duquesne University 1973

                                  A.B.
                                  Biology
                                  Thiel College 1964

 PROFESSIONAL       Associate Professor
 EXPERIENCE           1980 - present

                                  Director, Chemical Toxicology Program
                                  Department of Forensic Sciences
                                  The George Washington University
                                  1980 - 1981

                                  Assistant Professor
                                  Department of Forensic Sciences
                                  The George Washington University
                                  1975 - 1979

                                  Toxicologist
                                  Allegheny County Coroner's Office
                                  Pittsburgh, PA
                                  1968 - 1973

                                  Research Assistant in Gastroenterology
                                  Montefiore Hospital
                                  Pittsburgh, PA
                                  1965 - 1966

 PROFESSIONAL     The American Academy of Forensic Sciences
 MEMBERSHIPS        The Forensic Science Society
                                  The Society of Forensic Toxicologists
                                  The International Association of Forensic Toxicologists
                                  The Mid-Atlantic Association of Forensic Scientists
                                  Society of the Sigma Xi
                                  American Chemical Society
                                  The American Association for the Advancement of Science
 

PUBLICATIONS

R.L. Weaver, N.T. Lappas and W.F. Rowe, "Utilization of medically obtained evidence in cases of sexual assault:  Results of a survey", J. For. Sci., 23, 809-823 (1978).

N.T. Lappas, "Forensic science laboratories in the United States: A survey", J. For. Sci. Soc., 18, 171-180 (1980).

N.T. Lappas, "The Identification of human bloodstains by means of thin-layer immunoassay:  A preliminary report", J. For. Sci. Soc., 21, 301-305 (1981).

N.T. Lappas and M.E. Fredenburg, "The identification of human bloodstains by means of micro-thin-layer immunoassay procedure", J. For. Sci., 26, 564-569 (1981).

N.T. Lappas and W.T. Lee, "The use of tetramethylbenzidine in conjunction with thin-layer immunoassay for the detection of hemoglobin",  Forensic Serology News, 7, 1-2 (1981).

M.E. Fredenburg and N.T. Lappas, "The detection of opiates in urine by means of thin-layer immunoassay", J. Analyt. Tox., 6, 127-130 (1982).

L.C. Shughart and N.T. Lappas, "The detection of opiates in blood by means of thin-layer immunoassay", J. Analyt. Tox., 7, 209-212 (1983).

W. Sweeney, L.R. Goldbaum and N.T. Lappas, "Detection of benzoylecgonine in urine by means of UV spectrophotometry", J. Analyt. Tox., 7, 235-236 (1983).

E.M. Whitehead, M.E. Fredenburg and N.T. Lappas, "The detection of fetal hemoglobin in bloodstains by means of thin-layer immunoassay", J. For. Sci., 28, 888-893 (1983).

A.S. Masibay and N.T. Lappas, "Detection of p30 in seminal stains by means of thin-layer immunoassay", J. For. Sci., 29, 1173-1177 (1984).

N.T. Lappas, "Detection of opiates in biological material by means of thin-layer immunoassay", in Advances in Analytical Toxicology, ed., R.C. Baselt, vol. 1, Biomedical Publications, Foster City, Calif., 1984.

T.L. Stockham and N.T. Lappas, "Detection of opiates in postmortem tissues by thin-layer immunoassay", J. Analyt. Tox., 9, 194-196 (1985).

L. R. Goldbaum, D.H. Chace and N.T. Lappas, "Determination of carbon monoxide in blood by gas chromatography using a thermal conductivity detector", J. For. Sci., 31, 133-142 (1986).

D.H. Chace, L.R. Goldbaum and N.T. Lappas, "Factors affecting the loss of carbon monoxide from stored blood samples", J. Analyt. Tox., 10, 181-189 (1986).

G.J. Burin, N.T. Lappas and K.M. Brown, "An investigation of the effects of cocaine on neurulation in explanted chick embryos", Teratology, 35, 55-56A (1987).

K.G. Anitole, P.L. Stahle, C.S. Ridenour, N.T. Lappas and K.M. Brown, "Chlorpromazine-sensitive developmental processes in the sea urchin, Lytechinus pictus.  1.  Inhibition of cleavage, gastrulation and primary mesenchyme cell differentiation", Comp. Biochem. Physiol., 90C, 47-53 (1988).

K.G. Anitole, C.L. Butler, N.T. Lappas and K.M. Brown, "Chlorpromazine sensitive developmental processes in the sea urchin, Lytechinus pictus.  2.  Effects of neuroactive agents on the susceptibility of the gastrulation process to chlorpromazine", Comp. Biochem. Physiol., 90C, 55-60 (1988).

S. Dugan, S. Bogema, R.W. Schwartz and N.T. Lappas, "Stability of drugs of abuse in urine samples stored at -20°C", J. Analyt. Tox., 18, 391-396 (1994).

A. Grieshaber, A. Costantino and N. T. Lappas, "Stability of Phencyclidine in Stored Blood
Samples", J. Analyt. Tox., 22, 515-519 (1998).

A.  Papaconstantinou, T.H.Umbreit, B.R.Fisher, P.L.Goering, N.T. Lappas and K.E. Brown, "Bis-phenyl A induced increases in uterine weight and stress protein levels in uterine tissue morphology in ovariectomized  B6C3F1 mice are medicated through the E receptor", The Toxicologist, 54, 263, 2000.

A. Papaconstantinou, T.H.Umbreit, B.R.Fisher, P.L.Goering, N.T. Lappas and K.E. Brown, "Bisphenol A-induced increase in uterine weight and alterations in uterine morphology in ovariectomized B6C3F1 mice: role of the estrogen receptor". Toxicol Sci, 56, 332-339, 2000.
 
 
 

PRESENTATIONS

N.T. Lappas, "Graduate education in forensic sciences", an invited paper presented at the spring meeting of The Southern Association of Forensic Scientists, Tallahassee, FL, April 3, 1976.

J.W. Snyder and N.T. Lappas, "An estimate of the post-mortem interval by means of the in vitro glucose utilization by cerebral cortical homogenates", presented at the 12th semi-annual meeting of The Mid-Atlantic Association of Forensic Scientists, Pittsburgh, PA, September 29, 1978.

N.T. Lappas, C.E. O'Rear and W.F. Rowe, "Graduate education in the forensic sciences", presented at the 12th semi-annual meeting of The Mid-Atlantic Association of Forensic Scientists, Pittsburgh, PA, September 29, 1978.

A. Low-Beer and N.T. Lappas, "Detection of human chorionic gonadotropin in bloodstains", presented at the 13th semi-annual meeting of The Mid-Atlantic Association of Forensic Scientists, Gettysburg, PA, April 27, 1979.

A. Low-Beer and N.T. Lappas, "Detection of human chorionic gonadotropin in bloodstains by means of crossed electroimmunodiffusion", presented at the 32nd annual meeting of The American Academy of Forensic Scientists, New Orleans, LA, February 22, 1980.

N.T. Lappas, "The use of thin-layer immunoassay in forensic serology", presented at the 1st combined meeting of Forensic Scientist Associations, Louisville, KY, May 9, 1980.

N.T. Lappas, "The identification of human bloodstains by means of thin-layer immunoassay", seminar presented at the F.B.I., Washington, DC, May 16, 1980.

C.E. O'Rear, W.F. Rowe and N.T. Lappas, "From forensic science appreciation to forensic science education", Federation of Analytical Chemistry and Spectroscopy Societies, VII, Philadelphia, PA, September 29, 1980.

N.T. Lappas and M.E. Fredenburg, "Detection of morphine in urine by thin-layer immunoassay", presented at the annual meeting of The Society of Forensic Toxicologists, Toronto, Canada, October 3, 1980.

M.E. Fredenburg and N.T. Lappas, "The detection of fetal hemoglobin by means of thin-layer immunoassay", The Mid-Atlantic Association of Forensic Scientists, Arlington, VA, October 10, 1980.

N.T. Lappas and M.E. Fredenburg, "A novel method for the detection of morphine in urine", The Mid-Atlantic Association of Forensic Scientists, Arlington, VA, October 10, 1980.

M.E. Fredenburg and N.T. Lappas, "Application of thin-layer immunoassay in the forensic sciences", The Mid-Atlantic Association of Forensic Scientists, Charlottesville, VA, April 20, 1981.

E. Whitehead and N.T. Lappas, "The sensitivity and specificity of HbF detection in bloodstains by thin-layer immunoassay", The Mid-Atlantic Association of Forensic Scientists, Virginia Beach, VA, September 24, 1981.

W.T. Lee and N.T. Lappas, "The detection of ABO antigens in stains by thin-layer immunoassay", The Mid-Atlantic Association of Forensic Scientists, Virginia Beach, VA, September 25, 1981.

N.T. Lappas and M.E. Fredenburg, "The detection of opiates in urine by means of thin-layer immunoassay", American Academy of Forensic Sciences, Orlando, FL, February 10, 1982.

N.T. Lappas and E. Whitehead, "A novel method for the detection of HbF in bloodstains:  Thin-layer immunoassay", American Academy of Forensic Sciences, Orlando, FL, February 10, 1982.

N.T. Lappas and W.T. Lee, "ABO typing of bloodstains and saliva by thin-layer immunoassay", American Academy of Forensic Sciences, Orlando, FL, February 10, 1982.

N.T. Lappas, L. Shughart, A. DeAngelo and T. Stockham, "Thin-layer immunoassay:  A novel method for the detection of drugs in urine", Second International Conference on Immunopharmacology, Washington, DC, July 7, 1982.

A.S. Masibay and N.T. Lappas, "Detection of p30 in semen by means of thin-layer immunoassay", The Mid-Atlantic Association of Forensic Scientists, Rosslyn, VA, October 13, 1982.

L.C. Shughart and N.T. Lappas, "Detection of opiates in blood by means of thin-layer immunoassay", Society of Forensic Toxicologists, Rosslyn, VA, October 14, 1982.

A.S. Masibay and N.T. Lappas, "An inhibition thin-layer immunoassay for the detection of p30 in semen stains, "Forensic Science Symposium on the Analysis of Sexual Assault Evidence, F.B.I. Forensic Science Research and Training Center, Quantico, VA, July 8, 1983.

D.H. Chace, N.T. Lappas and L.R. Goldbaum, "Stability of carboxyhemoglobin in blood upon storage", The Mid-Atlantic Association of Forensic Scientists, Baltimore, MD, April 21, 1983.

D.H. Chace and N.T. Lappas, "Effects of various storage conditions on the stability of carboxyhemoglobin in blood", Sixth International Biodeterioration Symposium, Washington, DC, August 10, 1984.

N.T. Lappas, "Problems of interpretation in forensic toxicology", The Mid-Atlantic Association of Forensic Scientists, Ocean City, MD, October 4, 1986.

G.J. Burin, N.T. Lappas and K.M. Brown, "An investigation of the effects of cocaine on neurulation in explanted chick embryos", Teratology Society, Palm Springs, CA, March 27, 1987.

L. Tonelli, T. Phillips and N.T. Lappas, "Detection of ABO blood group substances in saliva by an ELISA method using monoclonal antibodies", The Mid-Atlantic Association of Forensic Scientists, Alexandria, VA, October 16, 1987.

N.T. Lappas, "Factors which influence interpretation in forensic toxicology: I. Age", The Mid-Atlantic Association of Forensic Scientists, Bethesda, MD, May 30, 1991.

S. Dugan, S. Bogema, N.T. Lappas, "The stability of drugs of abuse in frozen urine samples", An International Symposium on Forensic Toxicology, FBI Academy, Quantico, VA., June 16, 1992

J. Harris, B.F. Conley, J.W. Jones and N.T. Lappas, "Detection of ecgonine methyl ester, cocaine and benzoylecgonine in urine samples",  The Mid-Atlantic Association of Forensic Scientists, 1994.

S.H. Dugan, A.G. Costantino, S.Bogema and N.T. Lappas, "A study of the stability of cocaine, benzoylecgonine, ecgonine methylester, creatinine and other chemistries in urine", Society of Forensic Toxicologists, October 11, 1995.

L.R. Golbaum, J.H. Sklerov and N.T. Lappas, "The mecahnism of carbon monoxide toxicity", Experimental Biology ’96, Washington, D.C., April 15 , 1996.

K.K. Martin, J.J. Robinson and N.T. Lappas, "Urine sample dilution in a criminal defendant population in Washington, DC",  The Mid-Atlantic Association of Forensic Scientists, Harrisburg, Pa., May 9, 1996.

J.R. Iem, J.A. Sklerov and N.T. Lappas, "The detection of drugs of abuse in urine following unintentional exposure", The Mid-Atlantic Association of Forensic Scientists, Harrisburg, Pa., May 9, 1996.

A. Papaconstantinou, K.M. Brown, N.T. Lappas, B.R. Fisher and T.H. Umbreit, "Estrogenicity and heat shock proteins: Bisphenol A", Society of Toxicology, Seattle, WA, 1998.

N.T. Lappas, "Problems of interpretation in forensic toxicology", Department of Biology, University of Richmond, 1998.

N.T. Lappas, "Forensic toxicology: Drugs in the Courtroom", Department of Biology, University of Richmond, 2000.

N.T. Lappas, "Forensic toxicology: Drugs in the Classroom", Virginia Association of Independent Schools, Richmond, VA, November 6, 2000.
 

RECORD OF EXPERT TESTIMONY

Admitted as an expert in forensic toxicology on more than 80 occasions in the state courts of Maryland, Michigan, Pennsylvania, Virginia and West Virginia, the Superior Court of the District of Columbia and the United States District Court for the Eastern District of Virginia.