Professor T. J.
Manuccia
Research
Hardware, Algorithms
and Software tools for basic and applied neuroscience.
This general area has been one of my strongest research interests for the past several years. The hardware aspect of our research has been the development of optically switched planar microelectrode arrays for the recording and stimulation of populations of neurons. These arrays are produced lithographically and provide a several order of magnitude increase in the number of electrodes available from non-switched arrays.
The algorithm and software development aspect of this research involves the simulation and analysis of data from very large (eg, 105 neurons) networks of biologically realistic neuronal networks.
This PowerPoint presentation is a large ( 3 Meg) download, but gives an overview of much of our work in this area.
Potential applications of this work include neural prostheses, toxicological screening of candidate compounds in the drug discovery and development process, broad spectrum detection of chemical and biological warfare agents, as well as in fundamental neuroscience investigations.
Other research
interests / keywords:
Microelectrode arrays for biological neuronal networks
Development of algorithms and software to understand neural firing patterns
Simulation of very large biologically realistic neuronal networks
Optically switched low level analog electrical multiplexers
Microelectrode array applications in high throughput drug development & toxicology screening
Spectroscopy (including nonlinear, photoacoustic, ultra-high resolution, etc.)
Laser induced chemical processes including laser isotope separation
Novel laser applications in chemistry and biology
Laser microscopy
General biophysics and biomedical engineering
Please feel free to contact me for more information:
T. J. Manuccia
Professor of Engineering and Applied Science
Director ECE Laboratories
Dept. of Electrical and Computer Engineering
George Washington University
Phillips Hall, rm. 624-D
801 22nd Street, N.W.
Washington, DC 20052
Lab / Office:
Tompkins Hall, rm. 306-B
Email: manuccia AT gwu DOT edu (best
way to reach me)
ECE department main number: 202-994-6083
ECE department fax number: 202-994-0227