Faculty: Tom Manuccia

 

Thomas J. Manuccia

Professor of Engineering and
Applied Science
Main office:
Phillips Hall, rm. 624-D
801 22nd Street, N.W.
Washington, DC 20052

Lab office:
Tompkins Hall, rm. 306b
725 23rd street, N.W.
Washington, DC 20052

manuccia@gwu.edu

Personal home page:
http://home.gwu.edu/~manuccia/index2.html

 

 

Research
Selected Publications

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Research

R&D on hardware and algorithms for basic and applied neuroscience is one of my main interests.  The hardware aspect of our research has been the development of optically switched planar microelectrode arrays for the recording and stimulation of populations of neurons.  These arrays are produced lithographically and provide a several order of magnitude increase in the number of electrodes available from non-switched arrays.  The algorithm and software development aspect of this research is designed to understand neural firing patterns.  It involves the simulation and analysis of data from very large (eg, 105 neurons) networks of biologically realistic neuronal networks.

 

Potential applications of this work include neural prostheses, high throughput screening of candidate compounds in the drug discovery and development process, broad spectrum detection of chemical and biological warfare agents, as well as in fundamental neuroscience investigations.

 

Other research interests include: Optically switched low level analog electrical multiplexers, spectroscopy (including nonlinear, photoacoustic, ultra-high resolution, etc.), laser induced chemical processes including laser isotope separation, novel laser applications in chemistry and biology, various forms of laser microscopy.

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Selected Publications

  • Seaver, M; Peele, JR; Manuccia, TJ; Rubel, GO; and Ritchie, G.;  “Evaporation kinetics of ventilated water drops coated with octadecanol monolayers”;  J. Phys. Chem. v.96(15), pp. 6389‑94 (1992).
  • Seaver, M; Galloway, A; and Manuccia, TJ.;  “Water condensation onto an evaporating drop of 1‑butanol”;  Aerosol Sci. Technol. v.12(3), pp.741‑4 (1990).
  • Manuccia, TJ and Loda, RT.;  “The Laser Electron Microscope (LEM)”;  Berichte Bunsen Gesellschaft Physikalische Chemie v.93(3), pp.392‑6 (1989).
  • Seaver, M; Galloway, A; Manuccia, T.;  “Acoustic levitation in a free-jet wind tunnel”;  Rev. Sci. Instrum. v.60(11), pp.3452-9 (1989).
  • Seaver, M and Manuccia, TJ.;  “Transport Properties of Droplets in Gas Flows”;  1987 Naval Research Lab Review (1987).
  • Calvert, JM; Manuccia, TJ; and Nowak, RJ.;  “A polymeric solid-state electrochromic cell”;  Journal of the Electrochemical Society v.133(5), pp.951-3 (1986).
  • Seaver, M; Manuccia, TJ; and McDonald, JR.;  “Enhanced species selectivity in opto-acoustic detection”;  Chemical Physics Letters v.123(3), pp.164-8 (1986).
  • Duncan, MD; Reintjes, J; and Manuccia, TJ.;  “Imaging biological compounds using the coherent anti-Stokes Raman scattering microscope”;  Opt. Eng. v.24(2), pp.352-5 (1985).
  • Hsu, DSY and Manuccia, TJ.;  “Carbon isotope enrichment by retention of isotopic excitation selectivity in VV ladder climbing collisions”;  Chem. Phys. Lett. v.76(1), pp.16-20 (1980).
  • Manuccia, TJ.;  “Molecular Lasers”;  in the series Methods of Experimental Physics v.15(B) (1979).
  • Manuccia, TJ; Clark, MD; and Lory, ER.;  “Isotope separation by cw infrared laser enhanced reaction”;  J. Chem. Phys. v.68(5), pp.2271-6 (1978).
  • Frankel, D and Manuccia, TJ.;  “Collisionless 16 μm fluorescence in sulfur hexafluoride following 10 μm carbon dioxide laser pumping: comments on the vibrational quasicontinuum”;  Chem. Phys. Lett. v.54(3), pp.51-6 (1978).
  • Manuccia, TJ and Hsu, DS.;  “Deuterium enrichment by CW vibrational photochemistry of methane-economic considerations”;  Laser-Induced Processes in Molecules, pp.270-3 (1978).
  • Manuccia, TJ.;  “CW IR laser induced chemistry, isotope separation and related laser technology at NRL”;  Lasers in Chem.,  pp.210-215 (1977).
  • Manuccia, TJ; Clark, MD; and Lory, ER.;  “CW infrared laser isotope separation: C1+CH3Br(nu6) to HCl+CH2Br;  Optics Communications v.18(2), pp.219-20 (1976).
  • Manuccia, TJ; Stregack, JA; Harris, NW; and Wexler, BL.;  “14- and 16- mu gas dynamic CO2 lasers”;  Applied Physics Letters v.29(6), pp. 360-2.
  • Lory, ER; Bauer, SH; Manuccia, TJ.;  “Infrared laser augmented decomposition of H3PBF3;  IEEE Journal of Quantum Electronics v.QE-11(8), pp.714-15 (1975).
  • Wolga, GJ and Manuccia, TJ.;  “Hydrogen atom sources for electrically pulsed hydrogen halide lasers”;  IEEE Journal of Quantum Electronics v.QE9(1), p.193 (1973).
  • Manuccia, TJ and Wolga, GJ.;  “Velocity preservation- a quantitative technique for determining rates of fast inelastic collision processes”;  IEEE Journal of Quantum Electronics v.QE9(1), p.190 (1973).
  • Manuccia, TJ and Wolga, GJ.;  “The properties and application of diffraction gratings in frequency-selective laser resonators”;  IEEE Journal of Quantum Electronics v.QE-6(4), p.185 (1970).

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