Lijie Grace Zhang’s Lab

The Bioengineering Laboratory for Nanomedicine and Tissue Engineering

News

· Wei successfully defended his PhD dissertation titled “3D Printing and Electrospinning for Neural Tissue Engineering and Cancer Modeling Applications”, Congratulations, Dr. Zhu! (8/2017)

· Our lab has the following three conference presentations at the 54th Annual Technical Meeting of the Society of Engineering Science, July 25-28, Boston, MA. Dr. Zhang and Dr. Thomas J. Webster (Northeastern U.) chaired a symposium of 3D Bioprinting and Advanced Bioinks at the conference. (7/2017)

· S. Miao, H. Cui, M. Nowicki, N. J. Castro, J. Almeida, X. Zhou, W. Zhu, S. Lee, and L. G. Zhang. Novel 4D Printing of Topographical Constructs for Tissue Engineering

· H. Cui and L.G. Zhang. 3D Bioprinting of Self-healing Hydrogel for Tissue Regeneration

· W. Zhu, B. Boualam, and L. G. Zhang. 3D Bioprinting Cell-laden Nanocomposite for Cartilage Regeneration

· Margaret’s paper titled “Three-Dimensional Printing Techniques for Musculoskeletal Regeneration” was accepted by Nanotechnology. Congratulations, Margaret! (7/2017)

· Haitao’s paper entitled "3D Bioprinting for Organ Regeneration" was one of the most downloaded and read publications in Advanced Healthcare Materials in June, 2017. (7/2017)

· Dr. Zhang gave a technical talk entitled “Advanced Nano and Smart Materials Based 4D Bioprinting” at the Naval Future Force Science & Technology Expo on July 21, Washington, DC. (7/2017)

· DongNyoung’s paper titled “Directly induced neural differentiation of human adipose-derived stem cells using 3D culture system of conductive microwell with electrical stimulation” was accepted by Tissue Engineering Part A. (7/2017)

· Dr. Zhang gave a talk titled “Integrating 3D bioprinting and  nanomaterials for complex vascularized tissue regeneration” at the 91st ACS Colloids and Surface Science Symposium held at CUNY in New York City, July 9-12, 2017. (7/2017)

· Dr. Zhang was invited to serve as an associate editor for a new ASME Journal of Engineering and Science in Medical Diagnostics and Therapy. Here is the flyer for the journal. In addition, ASME has re-organized its biomedical related resources to form the Alliance of Advanced Biomedical Engineering (AABME) in order to “bring together practitioners in the growing discipline of biomedical engineering – across industry, research, academia, government, and more and to provide cutting edge content, tools and resources to address the specific needs of the biomedical engineering community.” (6/2017)

· Dr. Sakar, Dr Rao and Dr. Zhang received a GW Cross-Disciplinary Research Fund (CDRF) titled “Low Intensity Pulsed Ultrasound (LIPUS) and Microbubbles for Cartilage and Osteochondral Regeneration in 3D Printed Nanostructured Scaffolds”. (6/2017)

· Shida’s paper titled “4D printing of polymeric materials for tissue and organ regeneration” was accepted by Materials Today. Congratulations, Shida! (6/2017)

· Dr. Nowicki and PhD student Se-jun from our lab are featured in  GW SEAS Graduate Student Research video. Here is the link.(5/2017)

· Congratulations to Dr. Benjamin Holmes and his company Nanochon on winning the NSF SBIR Phase I grant! (5/2017)

· Dayun’s paper titled “The Specific Vulnerabilities of Cancer Cells to the Cold Atmospheric Plasma-Stimulated Solutions” was accepted by Scientific Reports. Congratulations, Dayun! (5/2017)

· Our lab formed three teams to participate 2017 GW Technology Commercialization Office Innovation Competition. (4/2017)

(1) 3D Printing Vasculature With Biomimetic Complexity for Cardiac Patches

(2) Engineered Vascularized Bone Constructs via Dual 3D Bioprinting

(3) Ultrasound-Activated Microbubbles for Cartilage Tissue Engineering

· Dr. Zhang and her NSF I-corps team were interviewed by GW Office of Innovation and Entrepreneurship with an intent to showcase the successful stories of GW researchers and promote the program to future participants. Here is the video link(4/2017) 

· Dr. Zhang was invited to give a seminar talk in the Department of Biomedical Engineering at  Case Western Reserve University. (4/2017)

· Dr. Debanjan Sarkar (SUNY at Buffalo) and Dr. Zhang co-organized the symposium “Multifunctional Biomaterial Design for Regenerative Tissue Engineering” at the Society For Biomaterials Annual Meeting, Minneapolis, MN. (4/2017)

· Xiuqi successfully defended her PhD dissertation titled “Synthesis and Diagnostic of Single and Multi-dimensional Nanomaterial in Arc Discharge Plasma”, she was co-advised by Prof. Keidar and Prof. Zhang. Congratulations, Dr. Fang! (3/2016)

· Wei’s paper titled  “3D Printing Scaffold Coupled with Low Level Light Therapy for Neural Tissue Regeneration” was accepted by Biofabrication. Congratulations, Wei! (3/2017)

· Wei received the prestigious Chinese Government Award for Outstanding Self Finance Students Abroad. Congratulations, Wei! (3/2017)

· Dr. Zhang was invited to serve as a member of NIH Biomaterials and Biointerfaces Study Section (BMBI), Center for Scientific Review, for the term beginning July 01, 2017 and ending June 30, 2021. She has also served as an ad hoc reviewer for Bioengineering, Technology, and Surgical Sciences (BTSS) study section since 2014. (3/2017)

· Our following six papers have been accepted and published recently (3/2017)

1. W. Zhu, T. Ye, S.J. Lee, H. Cui, S. Miao, X. Zhou, D. Shuai, and L.G. Zhang. Enhanced Neural Stem Cell Functions in Conductive Annealed Carbon Nanofibrous Scaffolds with Electrical Stimulation, Nanomedicine: Nanotechnology, Biology and Medicine, accepted.

2. J. George, H. Haghshenas, D. D’Hemecourt, W. Zhu, L.G. Zhang, V. Sorger. Scattering and Absorption Control in Biocompatible Fibers towards Equalized Photobiomodulation, Biomedical Optics Express, accepted (2017).

3. X. Zhou, M. Nowicki. H. Cui, W. Zhu, X. Fang, S. Miao, S. Lee, M. Keidar, and L.G. Zhang. 3D Bioprinted Graphene Oxide-Incorporated Matrix for Promoting Chondrogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells, Carbon, 116: 615–624 (2017).

4. D.N. Heo, N.J. Castro, S. Lee, H. Noh, W. Zhu, and L.G. Zhang, Enhanced bone tissue regeneration using 3D printed microstructure incorporated with hybrid nano hydrogel, Nanoscale, epub ahead of print (2017). *Cover image

5. D. Yan, H. Xiao, W. Zhu, N. Nourmohammadi, L.G. Zhang, K. Bian, and M. Keidar. The role of aquaporins in the anti-glioblastoma capacity of the cold plasma-stimulated medium, Journal of Physics D: Applied Physics, 50(5):055401 (2017).

6. H. Cui, M. Nowicki, J.P. Fisher and L.G. Zhang. 3D Bioprinting for Organ Regeneration. Advanced Healthcare Materials, 6(1):1601118 (2017).

· Dr. Zhang gave an invited seminar talk at Louisiana Tech University as part of their year-long New Frontiers in Biomedical Research Seminar Series. Here is the link. (3/2017)

· Margaret successfully defended her PhD dissertation titled “Three Dimensional Bioprinting and Micro/Nano-particle Integration for Complex, Gradient Osteochondral Tissue Engineering Scaffolds”, she was co-advised by Prof. Zhang and Prof. Plesniak. Congratulations, Dr. Nowicki! (2/2017)

· Welcome Prof. Li Fong Yau, Sam from the Department of Chemistry at National University of Singapore to have his sabbatical in our lab. (2/2017)

· Margaret received a Graduate Runner-Up Prize during the 2017 SEAS Student Research and Development Showcase. Congratulations, Margaret! (2/2017)

· Wei gave the following presentation in the 2017 Cellular and Molecular Bioengineering Conference in Kohala Coast, Hawaii, January 3-7, 2017.

· W. Zhu, B. Boualam and L. Zhang. 3D Bioprinting Mesenchymal Stem Cell-laden Construct with Core-shell Nanospheres for Cartilage Regeneration.

· Dr. Zhang takes one semester sabbatical leave at Harvard Medical School. This is hosted by Dr. Ali Khademhosseini’s lab. (1/2017)

· Dr. Zhang gave an invited talk at the IEEE EMBS Micro and Nanoengineering in Medicine Conference in Waikoloa, Hawaii, December 12-16, 2016. She also visited Dr. Yi Zuo’s lab in the Department of Mechanical Engineering at University of Hawaii at Manoa. (12/2016)

· Our following two papers were accepted by Tissue Engineering Part A. (12/2016)

· S. Lee, M. Nowicki, B. Harris and L.G. Zhang. Fabrication of a highly aligned neural scaffold via a table top stereolithography 3D printing and electrospinning, 

· T. Guo, J. Lembong, L.G. Zhang and J. P. Fisher. 3D Printing Articular Cartilage: Recapitulating the Complexity of Native Tissue.

· Dr. Zhang gave a seminar talk in the Department of Physics at GW. (12/2016)

· Dr. Zhang was invited to serve as a National Judge for the Siemens Competition. (12/2016)

· Haitao’s paper titled “3D Bioprinting for Organ Regeneration”  were accepted by Advanced Healthcare Materials. Congratulations, Haitao! (11/2016)

· Margarete and Xuan gave the following presentations in the 2016 ASME IMECE, Phoenix, AZ. (11/2016)

· M. Nowicki, M. Plesniak, and L. Zhang, 3D  Printing of Gradient Osteochondral Scaffolds using Soy Oil Resin.

· X. Zhou, N.J. Castro, W. Zhu, H. Cui, K. Sarkar, and L. Zhang, Enhancing Human Bone Marrow Mesenchymal Stem Cell Osteogenesis via Low Intensity Pulsed Ultrasound and 3D bioprinting Biomimetic Scaffolds.

· Dr. Zhang received 2016 ASME Sia Nemat-Nasser Early Career Award “for pioneering research in tissue engineering and biomechanics for the development of novel biologically inspired nanomaterials; and for research in the integration of nanobiomaterials with advanced 3-D bioprinting for complex tissue and organ regeneration.” The award ceremony took place at the Honors Assembly during the 2016 ASME IMECE annual conference in Phoenix, Arizona. Dr. Zhang also gave an invited award talk titled “Advanced Nano and Smart Materials Based 3D/4D Bioprinting”. Here is the award video link. (11/2016)

· Mitra’s paper titled “Lipid Coated Microbubbles and Low Intensity Pulsed Ultrasound Enhance Chondrogenesis of Human Mesenchymal Stem Cells in 3D Printed Scaffolds” was accepted by Scientific Reports. Congratulations, Mitra! (10/2016)

· Dr. Ben Holmes, our lab’s former PhD, was interviewed by GW today. Here is the story. (10/2016)

· Dr. Zhang was invited to give a keynote talk in the Bioscience and Bioengineering session at 2016 Biofabrication meeting in Winston-Salem, NC. (10/2016)

· Dr. Zhang was invited to give a seminar talk in the Stephenson School of Biomedical Engineering at the University of Oklahoma. (10/2016)

· Our lab’s paper titled “3D Bioprinting a Cell-laden Bone Matrix for Breast Cancer Metastasis Study” was accepted by ACS Applied Materials & Interfaces. Congratulations, Xuan! (10/2016).

· Shida’s 4D bioprinting paper was highlighted as the cover image of Tissue Engineering Part C in Volume 22 Issue 10. Congratulations, Shida! (10/2016)

· Dr. Zhang was invited to give a seminar talk in the Department of Biomedical Engineering at  Washington University in St. Louis. (10/2016)

· Dr. Zhang gave an invited talk in the Stem Cell Engineering track at the Biomedical Engineering Society Annual Meeting in Minneapolis, MN, October 5-8, 2016. Our lab also has the following presentations. (10/2016)

· H. Cui, W. Zhu, M. Nowicki, X. Zhou, A. Khademhosseini, and L. Zhang. Hierarchical Fabrication of Biomimetic Vascularized Tissue Constructs via Dual 3D Bioprinting and Regional Immobilization.

· S. Miao, W. Zhu, N. Castro, H. Cui, X. Zhou, J.P Fisher, and L. Zhang. 4D Printing Smart Biomedical Scaffolds with Novel Soybean Oil Epoxidized Acrylate.

· D. Heo, J. Kim and L. Zhang. Fabrication of highly conductive hydrogel-patterned nanofiber for bioelectronics device applications.

· W. Zhu, F. Masood and L. Zhang. 3D Printing Scaffold Containing Aligned Channels for Inducing Mesenchyamal Stem Cell Neuronal Differentiation.

· X. Zhou, W. Zhu, B. Holmes, S. Miao, H. Cui, and L. Zhang. A 3D Bioprinting Biomimetic Cell-laden Bone Matrix for Breast Cancer Metastasis Study.

· S. Lee, W. Zhu, and L. Zhang. Integrating Electrospun Microfibers into 3D Printed Scaffolds for Nerve Regeneration.

· H. Cui, W. Zhu, B. Holmes, M. Plesniak, and L. Zhang. Smart Self-modulatory Release System Based on Bioactive Coating Modified 3D Printed Perfused Scaffold for Vascularized Bone Regeneration.

· F. Masood, W. Zhu, and L. Zhang. Synergistically Inducing Neural Differentiation via 3D Printed Aligned Structure and Bio-inspired Immobilization of Growth Factors.

· S. Lee, and L. Zhang. 3D Bioprinting Nano Scaffold with Multi-walled Carbon Nanotubes for Improved Nerve Regeneration.

· X. Zhou, S. Lee, M. Nowicki, and L. Zhang. 3D Bioprinting Novel Graphene Oxide Scaffold for Improved Human Bone Marrow Mesenchymal Stem Cell Chondrogenic Differentiation.

· D. Heo, S. Lee and L. Zhang. Bone tissue regeneration using 3D printed microstructure incorporated with hybrid nano hydrogel.

· S. Miao, N. Castro, M. Nowicki, W. Zhu, J. Almeida, H. Cui, X. Zhou, and L. Zhang. 3D Laser Printing of Soybean Oil Epoxidized Acrylate for Highly Aligning Human Bone Marrow Mesenchymal Stem Cells.

· W. Zhu, R. Glazer and L. Zhang. 3D Printed Biomimetic Nanocomposite Matrix for the Study of Breast Cancer Bone Metastasis.

· Dr. John Fisher and Dr. Zhang co-organized the C-12 Symposium “3D printing implantable constructs for biomedical applications” at the 53rd Annual Technical Meeting of the Society of Engineering Science (SES) hosted by the University of Maryland. Haitao, Se-jun and Margaret also gave the following three talks in the conference. (10/2016)

· M. Nowicki, M. Plesniak and L. Zhang. 3D Bioprinting of Gradient Scaffolds for Cartilage Tissue Engineering.

· H. Cui and L. Zhang. In situ biomanufacturing of artificial blood vessels via 3D bioprinting.

· S. Lee, and L. Zhang. 3D bioprinting nano scaffold with multi-walled carbon nanotubes for improved nerve regeneration.

· Our lab’s paper titled “4D Printing Hierarchy Scaffolds with Highly Biocompatible Smart Polymers for Tissue Engineering Applications” was accepted by Tissue Engineering Part C. Congratulations, Shida! (9/2016)

· Our following two papers were accepted by Nanotechnology and Scientific Reports. (8/2016)

· M. Nowicki, N. Castro, M. Plesniak, and L.G. Zhang. 3D Bioprinting of Novel Osteochondral Scaffolds with Graded Microstructure, Nanotechnology, accepted.

· X. Zhou, N. Castro, W. Zhu, H. Cui, S. Miao, M. Aliabouzar, K. Sarkar and L.G. Zhang. Integrating Low Intensity Pulsed Ultrasound with 3D bioprinting Biomimetic Scaffolds for Improved Human Bone Marrow Mesenchymal Stem Cell Osteogenesis, Scientific Reports, accepted.

· Wei and Haitao gave the following presentations in the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Orlando, FL. (8/2016)

· H. Cui, M. Nowicki, and L. Zhang. In situ biomanufacturing of artificial blood vessels via 3D bioprinting.

· W. Zhu, and L. Zhang. Gelatin Methacrylamide Hydrogel with Graphene Nanoplatelets for Neural Cell-laden 3D Bioprinting.

· Wei won the Charles Gilmore Internship in Materials Science & Engineering. Congratulations, Wei! (7/2016)

· Dr. Zhang was invited to serve as the Study Section Review Committee Member of the Clinical and Translational Science Institute at Children’s National (CTSI-CN). (7/2016)

· Our following two papers were published in Advanced Healthcare Materials and Tissue Engineering. (7/2016)

· H. Cui, W. Zhu, M. Nowicki, X. Zhou, A. Khademhosseini and L.G. Zhang Hierarchical Fabrication of Engineered Vascularized Bone Biphasic Constructs via Dual 3D Bioprinting: Integrating Regional Bioactive Factors into Architectural Design, Advanced Healthcare Materials, doi: 10.1002/adhm.201600505 (2016).

· N. Castro, W. Tan, C. Shen and L.G. Zhang. Simulated Body Fluid Nucleation of 3D Printed Elastomeric Scaffolds for Improved Bone Regeneration, Tissue Engineering Part A, epub ahead of print (2016).

· Dr. Zhang attended the 11th Sino-US Symposium on Nanoscale Science and Technology held at Nanjin University. She also gave two seminar talks at the School of Medicine, Shanghai Jiao Tong University, and at the College of Mechanical Engineering, Zhejiang University in June. (6/2016)

· Dr. Kausik Sarkar (MAE), Dr. Zhang and Dr. Raj Rao (Department of Orthopedic Surgery) have received a Cross Disciplinary Research fund for their proposal titled “Low Intensity Pulsed Ultrasound (LIPUS) and Microbubbles for Cartilage Regeneration in 3D Printed Nanostructured Scaffolds”. (6/2016)

· Ben has been awarded the Best Entrepreneurial Lead among all 20 teams within the Arlington cohort of the National Science Foundation I-Corps program. Ben serves as one of the Entrepreneurial Leads for Team Nanochon along with Principal Investigator Dr. Zhang, Entrepreneurial Lead Nathan Castro, and Mentor Dick Fogel. Congratulations, Ben! (6/2016)

· Wei’s paper titled “3D Printed Bone Matrix for Characterization of Breast Cancer Cell and Osteoblast Interactions” was accepted by Nanotechnology,  Congratulations, Wei! (6/2016).

· Dr. Zhang gave an invited talk in the Nanomaterials for Biomedicine symposium at the 90th ACS Colloids and Surface Science Meeting at Harvard University, Cambridge, MA. (6/2016)

· Shida’s paper titled “4D Printing Smart Biomedical Scaffolds with Novel Soybean Oil Epoxidized Acrylate” was accepted by Scientific Reports, Congratulations, Shida! (5/2016)

· Congratulations to Ryan Herbst and Allison Below on winning the first prize Pelton Award for Outstanding Senior Project based on their 3D bioprinter design. This project was guided  by Dr. Nathan Castro. Thanks, Nathan! It is also the second time for our lab’s undergraduate students to win this highest honor of senior design competition at the GW school of Engineering. Here are pictures (5/2016)

· Dr. Zhang was invited to give a video presentation titled “3D printing nanomaterials for medical device applications" at a series of “Biomedical perspectives of novel biomaterials” in a celebration of 10 years of the International Journal of Nanomedicine. This video series were also presented at the World Biomaterials Congress in Montreal. (5/2016)  

· Welcome Nana Acquah and Benchaa Boualam, two 2016 APS STEP-UP Fellows, to do summer research in our lab. (5/2016)

· Our lab has the following three conference presentations: (5/2016)

· B. Holmes, K. Bulusu, M. Plesniak, and L. Zhang. A synergistic approach to the design, fabrication and evaluation of 3D printed micro and nano featured scaffolds for vascularized bone tissue repair. The TechConnect World Innovation Conference, Washington, DC, May 22-25, 2016.

· M. Aliabouzar, L. Zhang, K. Sarkar. Effects of ultrasound in presence of microbubbles on cartilage tissue regeneration in 3D printed scaffolds. Acoustical Society America annual meeting, Salt Lake City, Utah, May 23-27, 2016.

· B. Holmes and L. Zhang. 3D Printing Biomimetic Nanomaterials for Highly Efficient Vascularized Bone Development. The 10th World Biomaterials Congress, Montreal, Canada, May 17-22, 2016.

· DongNyoung’s paper titled “Multifunctional hydrogel coatings on the surface of implantable cuff electrode for improving electrode-peripheral nerve tissue interfaces” was accepted by Acta Biomaterialia. Congratulations, DongNyoung! (5/2016)

· The NSF has awarded Prof. Zhang a two year research grant for her proposal “4D Bioprinting of Smart Complex Tissue Constructs”. (5/2016)

· Se-jun’s paper titled “Development of Biomimetic 3D Printed Scaffolds with Core-shell Nanoparticles for Nerve Regeneration” was accepted by IEEE Transactions on Biomedical Engineering. Congratulations, Se-jun! (4/2016)

· Se-jun gave a presentation titled “3D Bioprinting Conductive Nano Scaffold With Multi-Walled Carbon Nanotubes for Improved Nerve Generation” in the 4th Annual Minnesota Neuromodulation Symposium in Minneapolis. (4/2016)

· Dr. Zhang gave an invited talk titled “Integrating 3D Printing and Nanotechnology for Complex Tissue Regeneration” in the Cardiothoracic Surgery Research Program of the National Heart, Lung and Blood Institute, NIH. (4/2016)

· Our Advanced Science paper about 3D bioprinted smart vascularized tissue was featured as the back cover image of the journal in volume 3 issue 8. It was also reported by MaterialsViewsChina.com. Here is the link. (4/2016)

· Dr. Zhang attended an NSF I-corps workshop held in Arlington, VA. The activity is related to Dr. Zhang’s NSF grant about 3D printing cartilage. Our I-corps team includes the other two lab members Dr. Holmes and Dr. Castro, who established a  company “NANOCHON”. Here is the company’s website. Sincerely hope that someday Nanochon will go public! (4/2016)

· Dr. Zhang gave two invited talks titled “3D Bioprinting Nanocomposite Scaffolds for Complex Tissue Regeneration in the symposium “Future Medicine: The Impact of 3D Printing”  and “Development of Biologically Inspired 3D Printed Biomaterial Scaffolds for Improved Stem Cell Differentiation” in the symposium “Manipulation of Substrate Properties for Improved Construction of Stem Cell-Based Biomaterials” at the American Association of Anatomists (AAA) Annual Meeting at Experimental Biology (EB), San Diego, April 2-5, 2016. Dr. Zhang also served as symposium chair of “Creating Structured Microenvironments for Regulating Stem Cell Differentiation” at the same conference. (4/2016).

· Congratulations, our lab’s third book “Neural Engineering: From Advanced Biomaterials to 3D Fabrication Techniques” is available online for pre-order now at Amazon and Springer! (3/2016)

· Congratulations, Margaret won the 1st place at the category of Engineering Group A on GW Research Days 2016! (3/2016)

· Haitao’s paper titled “The Self-modulatory Smart Release System Based on Bioactive Coating Modified 3D Printed Scaffold for Vascularized Bone Regeneration” was accepted by Advanced Science, Congratulations, Haitao! (3/2016).

· Dr. Zhang gave an invited talk titled “3D Bioprinting and Nanobioinks for Complex Tissue and Organ Regeneration” in the NSF Workshop on Additive Manufacturing for Health. (3/2016)

· Nathan successfully defended his PhD dissertation titled “Synthesis and Manufacture of 3D Nanocomposite Scaffolds for Osteochondral Regeneration via Table-top 3D Printing”, Congratulations, Dr. Castro! (3/2016)

· Dr. Zhang gave an invited talk titled “Integrating 3D Bioprinting and Nanomaterials for Complex Tissue Regeneration” in the FDA during the 19th US-Japan Cellular and Gene Therapy Conference. (3/2016)

· Dr. Zhang is invited to serve as the chair of Society for Biomaterials (SFB) membership committee for the second term (2016-2017). (3/2016)

· Se-Jun and Shida gave the following presentations in 2016 ASME NEMB, Houston, TX. (2/2016)

· S. Miao, W. Zhu, N. Castro, and L. Zhang. 4D printed biomimetic nano smart bone scaffold.

· S. Lee, T. Muss and L. Zhang. 3D Bioprinting Conductive Nano Scaffold with Multi-walled Carbon Nanotube for Improved Nerve Regeneration.

· Congratulations, Nathan won Honorable Mention For Continuing Excellence in the 10th GW SEAS Student Research and Development Showcase based on his presentation. Wei and Se-jun and Margaret also gave the following presentations. (2/2016)

· N. Castro and L. Zhang. Simulated body fluid nucleation of 3D printed elastomeric scaffolds for bone regeneration.

· S. Lee and L. Zhang. Development of 3D printed scaffolds with multi-walled carbon nanotubes to enhance neural stem cell growth and differentiationGW SEAS 10th Annual Research and Development Showcase, Washington, DC, February 24, 2016.

· M. Nowicki, N. Castro, M. Plesniak and L. Zhang. Three Dimensional Printing of Gradient Scaffolds to Bridge the Gap Between Bone and Cartilage for Osteochondral Defect Repair.

· W. Zhu and L. Zhang. 3D Printed Nanocomposite Matrix for the Study of Breast Cancer Bone Metastasis.

· Wei’s paper titled “Synergistic Effect of Cold Atmospheric Plasma and Drug Loaded Core-shell Nanoparticles on Inhibiting Breast Cancer Cell Growth” was accepted by Scientific Report. Congratulations, Wei! (2/2016).

· DongNyoung’s paper titled “Improvement of Osseointegration through Surface with Gold Nanoparticles for Dental Implant” was accepted by Journal of Colloid and Interface Science, Congratulations, DongNyoung! (2/2016).

· Nathan’s book chapter was published: N. Castro and L. Zhang, Chapter 12: Biomimetic Nanocomposite Hydrogels for Cartilage Regeneration, in: Nanocomposites for musculoskeletal tissue regeneration, H. Liu (Ed.), Woodhead Publishing Limited, 2016, 259-272. (2/2016)

· Our lab received a $50,000 NSF I-Corps grant titled “Nanochon, a commercial venture to 3D print regenerative implants for joint reconstruction . (1/2016)

· Dr. Zhang was invited to serve as the Associate Editor-in-Chief of International Journal of Nanomedicine (IJN). (1/2016)

· Our paper “B. Holmes, K. Bulusu, M. Plesniak and L. Zhang. 3D Printed Bone Scaffold with Interconnected Microvascular Mimicking Channels for Highly Efficient Bone Growth, ” was accepted by Nanotechnology, Congratulations, Ben! (12/2015)

· Ben Holmes successfully defended his PhD dissertation titled “Advanced Fabrication Techniques for Precisely Controlled Micro and Nano Scale Environments for Complex Tissue Regeneration and Biomedical Applications”, Congratulations, Dr. Holmes, the first Ph.D. from Zhang's lab! (11/2015)

· The undergraduate students from the GW’s Women Leadership Program (Science, Health & Medicine Cohort) with the program coordinator Dr. Carly N. Jordan visited Dr. Zhang's Bioengineering lab located in the SEH 3950. (11/2015)

· Our lab gave the following presentations in 2015 ASME IMECE, Houston, TX. Dr. Zhang also served as the chair of three sessions: Clinical Applications of Bioengineering II; General Biomedical and Biotechnology Applications I and II. (11/2015)

1) S. Lee, W. Zhu and L. Zhang. Development of novel 3D Printed hydrogel scaffold with core-shell nanoparticles for Nerve regeneration.

2) M Nowicki, N. Castro, M. Plesniak and L. Zhang. 3D Printing of Novel Gradient Osteochondral Scaffolds to Bridge the Gap Between Cartilage and Bone.

· Dr. Zhang was invited to serve as the member of Technical Program Committee of the 9th IEEE IEEE-NANOMED conference, Honolulu, Hawaii. She served as Symposium Chair of TS-13: Nanobiomaterials and 3D Nano/microfabrication Techniques for Biomedical Application. (11/2015)

· Our paper “W. Zhu, G. Teel, C. O’Brien, T. Zhuang, M. Keidar and L. Zhang. Enhanced Human Bone Marrow Mesenchymal Stem Cell Functions on Cathodic Arc Plasma Treated Titanium” was accepted by International Journal of Nanomedicine, Congratulations, Wei! (10/2015)

· Our lab gave the following presentations in 2015 BMES annual conference, Tampa, Florida. (10/2015)

1) W. Zhu, B. Harris and L. Zhang. Gelatin Methacrylate with Graphene Nanoplatelets for Targeting Neural Cell laden Printing

2) W. Zhu, S. Lee, M. Keidar, and L. Zhang. Integrating Cold Atmospheric Plasma and Core-shell Nanoparticle Drug Delivery System for Breast Cancer Treatment

3) J. Brennan, and L. Zhang. Electrospinning a Smart Material Polymer for the Development of a Thermo-Responsive Vascular Graft.

4) N. Castro, and L. Zhang. Simulated Body Fluid Nucleation of 3D Printed Elastomeric Scaffolds for Osteochondral Regeneration

5) M. Nowick, N. Castro, M. Plesniak, and L. Zhang. 3D Printing of Novel Gradient Osteochondral Scaffolds to Bridge the Gap between Cartilage and Bone

6) N. Castro, R. Patel, and L. Zhang. Design of a Novel 3D Printed Bioactive Nanocomposite Scaffold for Improved Osteochondral Regeneration

· Welcome Dr. Dong Nyoung Heo to join our lab! (10/2015)

· Nathan gave an invited talk about 3D printing for medicine in the GW School of Business on October 5th. (10/2015)

· Our paper “W. Zhu, B. Holmes, R.I. Glazer and L. Zhang. 3D Printed Nanocomposite Matrix for the Study of Breast Cancer Bone Metastasis” was accepted by Nanomedicine: Nanotechnology, Biology and Medicine, Congratulations, Wei! (9/2015)

· Congratulations, Dr. Zhang collaborated with Dr. Joseph O’Brien was awarded a  three year NSF Grant! The goal of this study is to create a novel 3D bioprinted construct for cartilage regeneration. (9/2015)

· Ben gave a presentation tilted with “Design and Experimental Evaluation of a 3D Printed Interconnected Microvascular Mimicking Network For Highly Efficient Bone Growth” in the 13th US National Congress of Computational Mechanics, San Diego. (7/2015)

· Our paper “N. Castro1, J. O’Brien and L. Zhang. Integrating Biologically Inspired Nanomaterials and Table-top Stereolithography for 3D Printed Biomimetic Osteochondral Scaffolds” was accepted by Nanoscale. Congratulations, Nathan! (7/2015)

· Our paper “C. Meals, B. Fox and L. Zhang. The Effect of Insertion Technique and Surgeon Experience on the Pullout Strength of Orthopedic Screws” was accepted by Current Orthopedic Practice, (7/2015)

· Our paper “W. Zhu, N. Castro, X. Cheng, M. Keidar and L. Zhang. Cold Atmospheric Plasma Modified Electrospun Scaffolds with Embedded Microspheres for Improved Cartilage Tissue Regeneration” was accepted by PloS One. Congratulations, Wei! (7/2015)

· Welcome Dr. Junghoon Kim to join our lab! (7/2015)

· Dr. Zhang gave a seminar talk invited by the Department of Biomedical Engineering, School of Medicine at Tsinghua University, Beijing, China. (6/2015)

· Welcome Tessa Muss and Benchaa Boualam, 2015 APS STEP-UP Fellows, to do summer research in our lab. (5/2014)

· Dr. Zhang gave the following presentation in the Second International Symposium on Vascular Tissue Engineering (ISVTE) to be held at Donghua University, Shanghai, China (5/2015)

· B. Holmes, K. Bulusu, M. Plesniak, and L. Zhang. A 3D printed Scaffold with a Microvascular Mimicking Network for Highly Efficient Bone and Vascular Growth

· Congratulations, Dr. Zhang was promoted to associate professor with tenure! (5/2015)

· Nathan and Wei gave the following presentations in the 4th ASME NEMB conference, Minneapolis, April 19-22, 2015.

1) N. Castro, R. Patel, and L. Zhang. Enhanced Human Bone Marrow Mesenchymal Stem Cell Behavior on Novel 3D Printed Osteochondral Nanocomposite Scaffolds.

2) W. Zhu, B. Holmes, R. Siegel and L. Zhang. 3D Printing a Nanostructured Bone Model for Breast Cancer Bone Metastasis Study.

· Wei, Ben, Nathan, and Se-jun gave the following presentations in the Society for Biomaterials Annual Meeting, Charlotte, North Carolina, April 15-18, 2015.

1) W. Zhu, C. O’Brien, J. George, V. Sorger, and L. Zhang. Integrating Low Level Light Therapy with 3D Printed Scaffolds for Improved Neural Tissue Regeneration.

2) B. Holmes, K. Bulusu, M. Plesniak, and L. Zhang. 3D Printed Bone Scaffolds with Biomimetic Nanomaterials and Vascular Mimicking Microchannels.

3) W. Zhu, S. Lee, M. Keidar, and L. Zhang. Combination of Cold Atmospheric Plasma and Nanoparticles Drug Delivery toward More Efficient Breast Cancer Cell Inhibition Therapy.

4) S. Lee, W. Zhu and L. Zhang. Development of 3D Printed hydrogel scaffold with embedded core-shell nanoparticles for nerve regeneration.

5) N. Castro and L. Zhang. 3D Printed Bioactive Nano Scaffolds for Osteochondral Regeneration.

· Dr. Zhang’s video presentation was published in a Nanomedicine series by Henry Stewart Talks, a leading international provider of online seminar-style presentations in the biomedical and life sciences. (4/2015)

· Congratulations, Dr. Zhang collaborated with Dr. Robert Siegel was awarded 2015 Katzen Cancer Research Center Innovative Cancer Pilot Research Study Grant! (4/2015)

· Dr. Zhang was invited by the Fischell Department of Bioengineering at University of Maryland, College Park to give a seminar talk titled “Integrating 3D Printing and Nanobiomaterials for Complex Tissue Regeneration”. (4/2015)

· Congratulations, Nathan received GW Conference Travel Grant for Graduate Students for the Society for Biomaterials Conference in Charlotte, North Carolina to be held through April 15 to April 18, 2015. (4/2015)

· Congratulations, Dr. Zhang received 2015 March of Dimes Foundation’s Gene Discovery and Translational Research Grant! (4/2015)

· Dr. Zhang is invited to serve as the chair of Society for Biomaterials (SFB) membership committee 2015-2016. (4/2015)

· Our paper “N. J. Castro, R. Patel, and L. Zhang. Design of a Novel 3D Printed Bioactive Nanocomposite Scaffold for Improved Osteochondral Regeneration” was accepted by Cellular and Molecular Bioengineering. Congratulations, Nathan! (4/2015)

· Benjamin Holmes was recently representing our lab to join a team of GWU researchers led by Vice President for Research, to pay a five-day visit to Hong Kong. He was invited to give presentations on osteochondral tissue repair and the commercialization of orthopedic devices in the Softlanding program, hosted by the Hong Kong Science and Technology Park (HKSTP). (3/2015)

· Congratulations Bobby Hollingsworth, a previous summer high school intern in our lab, has been awarded a Barry Goldwater Scholarship! (3/2015)

· Congratulations, Dr. Zhang received 2015 SEAS Outstanding Young Researcher Award! (3/2015)

· Dr. Zhang was invited by the Department of Biomedical Engineering at Northwestern University to give a seminar talk titled “Integrating 3D Printing and Nanobiomaterials for Complex Tissue Regeneration”. (3/2015)

· Welcome Dr. Shida Miao, Dr. Xuan Zhou and Dr. Haitao Cui to join our lab! (3/2015)

· Reporters from the Washington Business Journal (Feb 23rd) and the Washington Post (Feb 25th) paid a visit to our lab. (2/2015)

· Congratulations, Nathan and Margaret won two first place prizes in the experimental section and Ben won  the Entrepreneurship Runner-Up Prize in the 9th GW SEAS Student Research and Development Showcase based on their presentations. (2/2015)

1) 3D Printing of Bioactive Graded Nanostructured Scaffolds for Osteochondral Regeneration (Nathan).

2) Three-Dimensional Printing of Gradient Scaffolds to Bridge the Gap Between Bone and Cartilage for Osteochondral Defect Repair (Margaret).

3) 3D printed micro-nano scaffolds for design and growth of bone tissue with a vascular network  (Ben)

· Dr. Zhang was invited by the Department of Biomedical Engineering at University of Rochester to give a seminar talk titled “Integrating 3D Printing and Nanobiomaterials for Complex Tissue Regeneration”. (2/2015)

· Congratulations, our lab’s second book “ 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine” is available online now at Amazon and Elsevier ! (2/2015)

· Dr. Zhang was invited to serve as the International Advisory Board Member of the 11th International Conference "Medical Applications of Novel Biomaterials and Nanotechnology" of CIMTEC 2016 to be held in Perugia, Italy, June 5-10, 2016. (2/2015).

· Dr. Zhang was invited by the Department of Biology at The Catholic University of America to give a seminar talk titled “Integrating 3D Printing and Nanotechnology for Complex Tissue Regeneration”. (2/2015)

· Dr. Zhang was recognized as a 2015 Young Innovator in Cellular and Molecular Bioengineering Journal, invited to contribute a research article to a special issue of the journal. (1/2015)

· Our lab moves into the new Science and Engineering Hall (SEH). Here is the SEH  building  information. Here are the pictures of our new lab! (1/2015)

· News Archive.