My research interest includes the fundamentals and applications of soft-ionization mass spectrometry to solve biological problems.

In Situ ambient MS

I am currently interested in infrared-laser based ambient soft-ionization techniques such as atmospheric pressure (AP) infrared (IR) matrix-assisted laser desorption/ionization (MALDI) mass spectrometry to perform direct and rapid in situ analysis of biomolecules present in tissue, such as metabolites and lipids.

Imaging Atmospheric Pressure MALDI-MS

Atmospheric Pressure (AP) infrared (IR) matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) can be utilized to analyze molecules from tissue using its native water as the matrix. The AP IR-MALDI can be used for the real-time in vivo and in situ analysis of biomolecules in tissue without tedious sample preparation or complexity of loading the sample into a vacuum.

2D-SDS Gel electrophoresis

The classical proteomic technique, 2D-SDS Gel electrophoresis with MALDI (matrix-assisted laser desorption/ionization) mass spectrometry.

Other Research Interest

Other areas of my interest include broader aspects of mass spectrometric and related techniques such 2D gel electrophoresis, HPLC, GC, ion mobility spectrometry, etc.